The Library · Vol. 01Entry No. 36· Chapter 05

Griffonia simplicifolia

Griffonia simplicifolia

A woody climbing shrub native to West and Central Africa, where its seeds have been used in traditional medicine for generations. Griffonia simplicifolia seeds are the primary natural source of 5-HTP (5-hydroxytryptophan) — the direct precursor to serotonin, the neurotransmitter central to mood, sleep, and emotional well-being.

1
Active compounds
1
In our products
1
Clinical citations
05
Sleep & Mood
Griffonia simplicifolia (Griffonia simplicifolia) — botanical watercolor illustration

Griffonia simplicifoliaBotanical illustration

§ 1The molecules

Active compounds.

No.01

5-Hydroxytryptophan

Why this matters

  • 01Direct precursor to serotonin - converts to serotonin in the brain*
  • 02Supports positive mood and emotional well-being*
  • 03Promotes restful sleep by converting to melatonin at night*

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

§ 2Receipts

What the research shows.

In a recent clinical trial, older adults taking 100mg of 5-HTP daily for 12 weeks showed improvements in both cognitive scores and mood markers. As the direct precursor to serotonin, 5-HTP supports the brain's natural production of this important neurotransmitter.Nutrients, 2025

§ 3Where it lives

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— End of entry

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