No.01
Valerenic Acid
Why this matters
- № 01Interacts with GABA receptors to promote calm*
- № 02Supports relaxation without morning grogginess*
The Library · Vol. 01Entry No. 32· Chapter 05
Valerian Root
Valeriana officinalis
A flowering plant native to Europe and Asia, Valerian has been used since ancient Greece and Rome to promote relaxation and restful sleep. It's one of the most well-studied natural sleep aids.
2
Active compounds
2
In our products
2
Clinical citations
05
Sleep & Mood
§ 1The molecules
Active compounds.
No.02
Isovaleric Acid
Why this matters
- № 01Supports nervous system relaxation*
- № 02Promotes restful sleep*
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
§ 2Receipts
What the research shows.
“Systematic review and meta-analysis of 60 studies (n=6,894) on valerian for sleep and associated disorders. Meta-analysis of 10 placebo-controlled RCTs found a combined effect size of 0.36 for subjective sleep quality improvement. Subgroup analysis favored whole root preparations (ES=0.83) over extracts (ES=0.10). No severe adverse events reported.”Shinjyo et al., Journal of Evidence-Based Integrative Medicine, 2020
“Systematic review and meta-analysis of 16 RCTs (n=1,093) evaluating valerian for sleep quality. Dichotomous sleep quality outcomes from 6 studies showed valerian users had an 80% greater relative risk of reporting improved sleep (RR=1.8, 95% CI 1.2-2.9) compared to placebo, with no significant side effects.”Bent et al., American Journal of Medicine, 2006
— End of entry
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