No.01
Methylene Blue
Why this matters
- № 01Supports mitochondrial electron transport chain efficiency*
- № 02Promotes cellular energy (ATP) production*
- № 03Supports cognitive function and memory*
- № 04Antioxidant properties at low doses*
The Library · Vol. 01Entry No. 104· Chapter 11
Methylene Blue
Methylthioninium chloride
The first synthetic drug ever used in medicine (1891). At low doses, Methylene Blue acts as an electron carrier in mitochondria, supporting cellular energy production. It's being actively researched for cognitive and longevity benefits.
1
Active compounds
1
In our products
1
Clinical citations
11
Longevity & Cellular Energy
Methylthioninium chlorideBotanical illustration
§ 1The molecules
Active compounds.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
§ 2Receipts
What the research shows.
“In a double-blind, placebo-controlled study, a single dose of methylene blue improved memory retrieval by 7% and increased brain activity during attention and memory tasks in healthy adults. As the first fully synthetic drug in medicine (1876), methylene blue has over a century of clinical use and supports mitochondrial function and cellular energy production.”Rodriguez et al., Radiology, 2016
From the Library · Vol. 01
Know exactly what
you're taking.
Every compound in your stack — sourced, dosed, and cited. No proprietary blends. Browse the science behind the bottles.
118Ingredients
180Compounds
14Chapters
Browse by chapter
A cross-section of the library — six chapters in view, plus eight more inside.Showing 12 · Browse all 118 →
We publish every dose, every source, every paper we leaned on. An informed customer is our only kind.
Browse the full libraryFrom the Journal
Keep reading.
Journal · nad-plus
Apr 10, 2026
6 Biomarkers of Aging You Can Actually Influence
NAD+ decline, CoQ10 depletion, telomere shortening, mitochondrial Complex IV inefficiency, collagen loss, and phosphocreatine decline — six measurable markers of biological aging and the compounds that influence each one.
Read article→
Journal · methylene-blue
Mar 12, 2026
Methylene Blue: From Lab Stain to Mitochondrial Biohack
Methylene blue has been a WHO essential medicine since 1876. At low doses it functions as an alternative electron carrier in the mitochondrial ETC — here's the mechanism, the human evidence, and the safety profile that makes this an advanced-only compound.
Read article→
— End of entry
Put Methylene Blue to work.
Browse the products it’s in, or build a stack around the goal it serves best.