The Library · Vol. 01Entry No. 19· Chapter 03

Chinese Club Moss

Huperzia serrata

A primitive, slow-growing moss native to mountain forests of China and Southeast Asia, used in Traditional Chinese Medicine for centuries. Huperzia serrata is the natural source of huperzine A — a potent acetylcholinesterase inhibitor that protects acetylcholine, the neurotransmitter central to learning and memory.

1
Active compounds
2
In our products
2
Clinical citations
03
Nootropics & Brain
Chinese Club Moss (Huperzia serrata) — botanical watercolor illustration

Huperzia serrataBotanical illustration

§ 1The molecules

Active compounds.

No.01

Huperzine A

Why this matters

  • 01Inhibits acetylcholinesterase - protects acetylcholine from breakdown*
  • 02Supports learning and memory*
  • 03Promotes mental clarity*

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

§ 2Receipts

What the research shows.

Meta-analysis of 20 RCTs (n=1,823) evaluating Huperzine A for Alzheimer's disease. Huperzine A significantly improved cognitive function on MMSE at 8, 12, and 16 weeks, and improved activities of daily living at 6, 12, and 16 weeks versus placebo. Most trials used 0.2-0.4 mg/day.Yang et al., PLoS ONE, 2013
Double-blind, placebo-controlled RCT of 103 patients with Alzheimer's disease. 0.2 mg Huperzine A taken twice daily for 8 weeks improved memory (p<0.01), cognition (p<0.01), and behavioral function (p<0.01). 58% of treated patients showed improvement versus 36% on placebo.Xu et al., Acta Pharmacologica Sinica, 1995
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180Compounds
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