Bovine Colostrum

Bos taurus colostrum

The nutrient-dense first milk produced by cows within the initial 24–72 hours after calving. Bovine colostrum is rich in immunoglobulins (primarily IgG), lactoferrin, growth factors (IGF-1, TGF-β), and proline-rich polypeptides that have been studied for their role in immune modulation and gut barrier integrity.

Active Compounds

Immunoglobulin G (IgG)

  • Supports passive immune defense in the gastrointestinal tract*
  • Helps maintain gut barrier integrity and healthy intestinal permeability*

Lactoferrin

(Lactotransferrin)
  • Supports the body's natural immune response through iron-binding activity*
  • Helps maintain a healthy microbial environment in the gut*

Growth Factors (IGF-1, TGF-β)

  • Supports tissue maintenance and healthy cellular renewal*
  • Helps maintain the structural integrity of the intestinal lining*

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

What the Research Shows

A randomized, double-blind, placebo-controlled trial in ICU-hospitalized patients found that bovine colostrum supplementation improved markers of intestinal permeability (plasma endotoxin and zonulin) and reduced gastrointestinal complications compared to placebo.

Source: Nutrition, 2019

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A randomized, triple-blind, placebo-controlled trial in medical university students found that low-dose bovine colostrum (0.5–1.0 g/day) significantly reduced the frequency and severity of upper respiratory tract infection symptoms compared to placebo over a 107-day period.

Source: Nutrients, 2023

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Products with Bovine Colostrum

Colostrum Powder

Colostrum Powder

2,300 mg(25% IgG (575mg))
$29.90
Colostrum Capsules

Colostrum Capsules

500 mg(30% IgG (150mg))
$26.90
From the Journal

Keep reading.

Bovine Colostrum: Immunoglobulins, Growth Factors, and the Gut Barrier Compound That Isn't a Probiotic
Journal · bovine-colostrumApr 10, 2026

Bovine Colostrum: Immunoglobulins, Growth Factors, and the Gut Barrier Compound That Isn't a Probiotic

Colostrum isn't a probiotic. It doesn't contain live bacteria. What it contains — immunoglobulins, lactoferrin, and growth factors — operates through mechanisms that are fundamentally different from anything in the probiotic category, and arguably more relevant to the modern gut-barrier problem.

Read article→

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Tanner, Chief Mushroom Officer

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