Cordyceps Mushroom

In a clinical trial, active adults who supplemented with Cordyceps militaris for 3 weeks showed significant improvements in VO2max compared to placebo. Clinical research shows Cordyceps supplementation significantly improves oxygen utilization during physical activity.

Reishi Mushroom

In an 84-day clinical trial, healthy adults taking Reishi β-glucan showed significant improvements in multiple immune markers, including enhanced T-cell populations and natural killer cell activity. Traditionally revered for its calming properties, Reishi has been used for centuries to support restful sleep and relaxation.

Lion's Mane Mushroom

In a 16-week clinical trial, adults with mild cognitive concerns who took 3g of Lion's Mane daily showed significant improvements in cognitive function compared to placebo. Multiple studies suggest Lion's Mane may support mental clarity through its unique ability to stimulate nerve growth factor production.

Turkey Tail Mushroom

Phase I clinical trial (n=11) evaluating Trametes versicolor (turkey tail) mushroom at escalating doses (3, 6, or 9 g/day) in women with breast cancer post-radiation. Turkey tail polysaccharopeptide (PSP) supplementation for 6 weeks significantly enhanced NK cell activity and increased CD8+ T-cell and CD19+ B-cell counts in a dose-dependent manner.

Turkey Tail Mushroom

Systematic review of 13 RCTs evaluating polysaccharide-K (PSK) and polysaccharopeptide (PSP) from Trametes versicolor as adjuvant cancer therapy. PSK (3 g/day) alongside chemotherapy significantly improved 5-year survival rates in gastric and colorectal cancer patients, mediated through beta-glucan activation of innate and adaptive immunity.

Chaga Mushroom

Chaga has been used in traditional medicine for centuries, particularly in Russia and Northern Europe. Laboratory studies have identified powerful antioxidant compounds including polyphenols and melanin. Preclinical research suggests Chaga may support the body's natural defenses against oxidative stress.

Cordyceps Mushroom

In a clinical trial, active adults who supplemented with Cordyceps militaris for 3 weeks showed significant improvements in VO2max compared to placebo. Clinical research shows Cordyceps supplementation significantly improves oxygen utilization during physical activity.

GABA

Systematic review of 14 placebo-controlled human trials examining oral GABA supplementation for stress and sleep. Found limited evidence supporting stress reduction (including EEG alpha-wave increases and salivary IgA maintenance) and very limited evidence for sleep benefits. Doses ranged from 100-300 mg.

GABA

Human crossover study (n=13) found that a single oral dose of GABA (100 mg) significantly increased alpha waves and decreased beta waves on EEG within 60 minutes, indicating enhanced relaxation and reduced anxiety. A second study (n=8) showed GABA maintained salivary IgA levels under acute stress versus placebo.

Ginkgo Biloba

Clinical trials involving over 2,500 patients demonstrate that Ginkgo biloba extract (240mg/day) supports cognitive function in adults experiencing age-related cognitive changes. The standardized EGb 761® extract has been shown to support memory, daily functioning, and overall mental clarity.