Piperine
Why this matters
- № 01Increases bioavailability of other compounds by up to 2000%*
- № 02Enhances nutrient absorption in the gut*
- № 03Supports healthy metabolism*
Piper nigrum
More than just a spice - Black Pepper contains piperine, a powerful bioavailability enhancer that significantly increases the absorption of other nutrients and compounds.

Piper nigrumBotanical illustration
§ 1The molecules
Why this matters
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
§ 2Receipts
“Landmark crossover study in humans (n=8 per group) demonstrating that co-administration of 20 mg piperine with 2 g curcumin increased curcumin bioavailability by 2,000%. A separate arm showed 20 mg piperine increased beta-carotene bioavailability by 60%. The mechanism involves inhibition of hepatic and intestinal glucuronidation.”Shoba et al., Planta Medica, 1998
“Review of piperine's pharmacokinetic enhancement effects across multiple human and animal studies. Piperine (5-20 mg) significantly increases the bioavailability of curcumin, resveratrol, beta-carotene, CoQ10, and several pharmaceutical drugs by inhibiting CYP3A4, CYP1A1, and P-glycoprotein efflux transporters.”Kesarwani & Gupta, Asian Pacific Journal of Tropical Biomedicine, 2013
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