The Library · Vol. 01Entry No. 148· Chapter 14

Polydeoxyribonucleotide (PDRN)

Polydeoxyribonucleotide

A bioactive DNA polymer (50–1,500 kDa) derived from salmon (Oncorhynchus keta) sperm cells. PDRN activates adenosine A2A receptors on fibroblasts and keratinocytes, stimulating cellular regeneration, collagen synthesis, and angiogenesis. It has an extensive clinical history in wound healing and is now widely used in aesthetic dermatology for skin rejuvenation.

1
Active compounds
1
In our products
1
Clinical citations
14
Topicals & Botanicals

§ 1The molecules

Active compounds.

1 compound · 3 statements

No.01

Deoxyribonucleotide Fragments

Why this matters

  • № 01Supports fibroblast activity and collagen synthesis through adenosine A2A receptor activation*
  • № 02Promotes skin cell renewal and healthy tissue regeneration*
  • № 03Helps improve skin texture, elasticity, and overall radiance*

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

§ 2Receipts

What the research shows.

1 citation

“In a double-blind, randomized, placebo-controlled study, patients receiving intramuscular and subcutaneous PDRN after skin graft procedures showed significantly greater wound re-epithelialization at the donor site compared to placebo over a 10-day treatment course.”Current Medical Research and Opinion, 2001

§ 3Where it lives

Find Polydeoxyribonucleotide (PDRN) in

1 product

PDRN Brightening Serum
PDRN Brightening Serum
†
$33.90

— End of entry

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