Resveratrol
Activate longevity. Protect your heart.
60 Servings·$0.35/serving
+ $4.50 shipping·free shipping over $35
Per Serving
600mg of trans-resveratrol from Polygonum Cuspidatum root. Activates sirtuin longevity pathways, supports arterial flexibility, and promotes mitochondrial biogenesis. The longevity molecule — clinically dosed.
- ■Longevity Pathways: Activates sirtuins — the cellular repair signals linked to caloric restriction.
- ■Heart Health: Supports arterial flexibility and nitric oxide production.
- ■Antioxidant: Targets lipid peroxidation in cell membranes.
- ■Mitochondria: Promotes biogenesis — your cells build more power plants.
What's Inside
Ingredients are the natural sources in this product. Compounds are the bioactive molecules within each ingredient that provide specific health benefits.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Recommended Usage
Take daily with a meal
600mg of trans-resveratrol from Polygonum Cuspidatum root.
Sirtuin pathways activate
Resveratrol mimics caloric restriction signals, triggering cellular repair and mitochondrial biogenesis.
Longevity and heart health improve
Consistent use supports arterial flexibility, antioxidant defense, and healthy aging.
Smart Cycling Protocol
Resveratrol activates SIRT1 (a NAD⁺-dependent deacetylase) and inhibits PDE enzymes, raising cAMP levels. Continuous SIRT1 activation can deplete the cellular NAD⁺ pool and trigger compensatory PDE upregulation, blunting the cAMP-mediated benefits over time.
Mechanism Diagrams
Resveratrol
Resveratrol
Resveratrol follows a 5 days on, 2 days off weekly rhythm. SIRT1 activator. Intermittent dosing mimics hormetic stress pattern for optimal sirtuin activation.
During rest days
The off period allows NAD⁺ pools to replenish via the salvage pathway (NAMPT enzyme) and PDE expression to normalize, so the next on-period achieves full SIRT1 activation and cAMP elevation.
Recovery timeline
~48 hours
NAD+ pools replenish via the NAMPT salvage pathway; PDE expression normalizes
preclinicalCycling threshold
≥250mg/day
At ≥250mg, significant CYP1A2 enzyme induction and SIRT1 activation. Chronic use may induce its own metabolism (autoinduction). Below 100mg acts as antioxidant support.
From the Journal
What to Expect
This shows how the product's benefits typically develop over time — from fast-acting acute effects to steady foundational support.
Steady, cumulative support that builds over consistent daily use.
Illustrative only — not a medical claim. Individual results may vary.
FAQ
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"I was spending hundreds a month on supplements and still guessing — wrong doses, wrong timing, products that stopped working after a few weeks. The industry sells you 30 bottles and leaves you to figure it out. I built Nomad to fix that: transparent dosing, protocols that cycle so your body stays responsive, and a system that tells you exactly what to take each day. Every product I ship is something I take myself."
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